Andreas Manz
ISAS - Institute for Analytical Sciences
Dortmund, Germany
a.manz@isas.de
Microfluidic chips have been developed and applied to various fields. Particularly, fast separations and chemical reactions for use in analytical chemistry or clinical diagnostics context have been of interest [1]. Scaling laws predict a higher mass and heat transport for smaller dimensions. However, there is a trade-off between internal volumes and detection limits. Key applications include drug discovery [2], systems biology and regenerative medicine research.
In this presentation, I will briefly review scaling laws, show examples of microfluidic chips for electrophoresis, chemical synthesis, elaborate on work-in-progress with cell differentiation and give an example how mishaps turn out to be quite interesting….
References
[1] D.Janasek, J.Franzke, A.Manz
Nature 442, 374-380 (2006)
P.S.Dittrich, K.Tachikawa, A.Manz
Anal. Chem. 78, 3887-3908 (2006)
[2] P.S.Dittrich, A.Manz
Nature Reviews Drug Discovery, 5, 210-218 (2006)
